Technology

Introducing the Syntensor Terminal, a self-service app for predicting clinical trial outcomes for small molecules with greater than 80% accuracy. To predict trial outcomes, the Syntensor platform first simulates a comprehensive suite of potency and ADMET assays; collectively, these two areas account for 60-70% of clinical trial failures. The model considers these predictions along with the burden of evidence for the drug's mechanism of action in the disease and trial design features to predict a probability of progression from one clinical trial stage to the next.

Terminal

Value

  • Make more confident investment decisions: The platform predicts trial outcomes with > 80% accuracy based on predicted chemical properties and biological features, combined with trial design factors. Trial outcomes are a major driver of biotech stock price.
  • Gain insights into molecules with limited information in the public domain: The model generalizes to novel molecules and mechanisms of action

Key Features

  • Find predicted outcomes for hundreds of thousands of small molecule clinical trials.
  • Search for trials by stock ticker, clinical trial ID, drug, indication, and/or sponsor.
  • In development: Understand historic performance for a mechanism of action in an indication
  • In development: Understand the main reasons for the model's predictions

Contributor organizations

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  • Profile image of Mila
  • Profile image of Stanford University
  • Profile image of University of Michigan